a decreasing trendp < 0.001
Furthermore, anal cancer highlighted a Joinpoint with a decreasing trend from 2008 to 2014 (APC = −3.7%, 95% CI = −4.7, −2.8; p < 0.001) and a slightly increasing trend in the period 2014–2018 (APC = 1.3% 95% CI = −0.6, 3.3; p = 0.136).