Oral Administration of Lipopolysaccharide Enhances Insulin Signaling-Related Factors in the KK/Ay Mouse Model of Type 2 Diabetes Mellitus.

Int J Mol Sci · 2023 · PMC10003108 · PMID 36902049

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an increasing trendno p-value reported

In addition, the expression level of insulin receptor ( Ir ), which is involved in insulin signaling to upregulate Glut4 expression, showed an increasing trend in the LPS (+) group compared with that in the LPS (−) group ( Figure 5 c).

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a decreasing trendno p-value reported

Regarding blood glucose parameters, the fasting blood glucose showed a decreasing trend in the LPS (+) group compared with that in the LPS (−) group, and HbA1c decreased significantly in the LPS (+) group when compared with that in the LPS (−) group ( Figure 2 c,d).

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