Changes in mortality among patients with chronic obstructive pulmonary disease from the 1990s to the 2000s: a pooled analysis of two prospective cohort studies.

BMJ Open · 2023 · PMC10008372 · PMID 36882247

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a positive trendno p-value reported

Differences in ICS compounds and devices may have affected these results, but we did not observe a positive trend of ICS use on survival in the present analysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.