The burden of liver cirrhosis and underlying etiologies: results from the Global Burden of Disease Study 2019.

23 However, our study found that ASIR and ASPR for liver cirrhosis due to HCV in China Mainland showed an increasing trend, which is consistent with previous studies, and may be due to the relatively delayed initiation of the HCV screening program and the variety of HCV infection routes in these years. 24 , 25 It can be expected that the incidence and prevalence of HCV-related cirrhosis in China Mainland would decline in the next 5 years, as estimated by the trajectory of HCV epidemiology in Egypt.

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Liver cirrhosis burden in different countries and territories Among all the countries and territories, The Republic of Moldova had the highest ASIR of liver cirrhosis both in 2009 and 2019, despite displaying a decreasing trend with an EAPC of −2.55 (95% CI: −2.98 to −2.12) (Figure 2 A, D).

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