Use of a Liver-Targeting Immune-Tolerogenic mRNA Lipid Nanoparticle Platform to Treat Peanut-Induced Anaphylaxis by Single- and Multiple-Epitope Nucleotide Sequence Delivery.

However, prophylactic administration of mAra h2#4/LNP or mAra h2#4/LNP-Man prevented hypothermia onset, with the impact of mannose-decorated particles highly significant ( p < 0.001) compared with nondecorated LNP ( p < 0.01) ( Figure 7 C).

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