The estimated coefficients were used to calculate trends via the Annual Percent Change (APC) parameter and respective 95% confidence intervals (CI), calculated based on the following formula: A P C = [ - 1 + 10 b 1 x 100 ; C I 95 % = - 1 + 10 b 1 m i n x 100 ; 1 + 10 b 1 max ] x 100 A positive APC indicates an increasing trend for the time series analyzed, a negative value a decreasing trend, and no statistically significant difference is classified as stationary [ 31 ].
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Evolution of research funding for neglected tropical diseases in Brazil, 2004-2020.
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