Anti-proliferative effect of melatonin in human hepatoma HepG2 cells occurs mainly through cell cycle arrest and inflammation inhibition.

Sci Rep · 2023 · PMC10020432 · PMID 36928762

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

highly significantP < 0.01actually significant

Our results validated that, melatonin shows anti-proliferative action through preserving cells in G0/G1 phase ( P < 0.001) that is associated with a highly significant increase in the expression level of the P53 gene ( P < 0.01).

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