Barely Significant
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Immune checkpoint inhibitors combined with tyrosine kinase inhibitors or immunotherapy for treatment-naïve metastatic clear-cell renal cell carcinoma-A network meta-analysis. Focus on cabozantinib combined with nivolumab.

Front Pharmacol · 2022 · PMC10020696 · PMID 36937206

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highly significantno p-value reported
OS is a highly significant clinical endpoint—both from the patient’s and the clinician’s perspective—and is a widely accepted measure of benefit that can be easily and accurately assessed.

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