However, if rFSH is administered from day 8 onwards, a nonsignificant trend toward premature progesterone elevation was detected, with no significant difference between corifollitropin and daily rFSH. 16 Finally, multiple pregnancies tended to be more frequent for corifollitropin alfa (+ 4.4% absolute risk increase) than for daily rFSH in the ENGAGE Trial. 3 Flexible
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Corifollitropin Alfa for Controlled Ovarian Stimulation in Assisted Reproductive Technologies: State of the Art.
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