highly significantP < 0.001
We also found a highly significant relationship between plasma-EV number and peripheral blood neutrophil number ( R 2 = 0.753, P < 0.001) at time of presentation ( Figure 2D ), consistent with a possible role for plasma EVs in neutrophil mobilization post-AMI. 3.4 Human VCAM-1+ plasma EVs are enriched at time of presentation with AM