The estimated proportion of the adaptive haplotype is 0.36 [95% confidence interval (CI), 0.21 to 0.52; n = 19] for the ancient plateau individuals older than 2500 B.P., 0.47 (95% CI, 0.33 to 0.61; n = 24) for the 2400- to 1900-year-old plateau individuals, and 0.59 (95% CI, 0.47 to 0.71; n = 37) for the more recent 1600- to 700-year-old plateau individuals, showing an increasing trend from 3000 to 700 B.P.
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