The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.

Elife · 2023 · PMC10023161 · PMID 36877136

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A more in-depth analysis of the scRNA-seq dataset ( Jackson-Weaver et al., 2020 ), revealed a positive and highly significant correlation between Tbx5 and pCharme ( Figure 1G , left panel) in CM, with some differences occurring across the CM cluster subtypes (see, for instance, CM-IVS/CM-OFT, Figure 1G , right panel).

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