Polygoni Multiflori Radix interferes with bile acid metabolism homeostasis by inhibiting <i>Fxr</i> transcription, leading to cholestasis.

Front Pharmacol · 2023 · PMC10025474 · PMID 36950015

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an increasing trendno p-value reported

Compared with the control group, all serum indices of liver injury showed an increasing trend and reached a significant difference in the eighth week.

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