Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone.

Front Endocrinol (Lausanne) · 2023 · PMC10025507 · PMID 36950685

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a decreasing trendp<0.05actually significant

The mRNA levels of the proteins associated with testosterone synthesis in Leydig cells of aged mice showed a decreasing trend, among which the difference in Star (p<0.05), Cyp11a1 (p<0.05), and Cyp17a1 (p<0.01) had statistically significances ( Figure 1G ).

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