An improved medium formulation for efficient <i>ex vivo</i> gene editing, expansion and engraftment of hematopoietic stem and progenitor cells.

The HSC-preserving effect exerted by medium B and C was specific to the primitive stem cell pool, as no significant differences with the other media were observed in the MPP fraction; however, we did notice a favorable trend for media A and D in the preservation of MPPs after 6 days of culture, as already observed in Figure 1 ( Figure S2 B).

also in 993 other papers