Exercise suppresses neuroinflammation for alleviating Alzheimer's disease.

J Neuroinflammation · 2023 · PMC10026496 · PMID 36935511

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In AD, the antioxidant effect can reveal a decreasing trend with the decrease of nuclear factor-related factor 2 (Nrf2) level [ 150 ], as confirmed that Dl-3-n-butylphthalide (NBP) inhibits NLRP3 inflammasomes and delays the pathological process of AD through the Nrf2-TXNIP-TRX signal pathway [ 151 , 152 ].

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