highly significantP =.001
An App Use Frequency of Fewer Than Once Every 5 Weeks Leads to a Significant Amelioration of Quality of Life, Pain, Activity, and Extent of Eczema When analyzing the outcomes in regard to app use frequency, the subgroup with an app use frequency of <20% showed a highly significant improvement in quality of life (DLQI) compared with the control group (V2: r =–1.23; P =.001; V3: r =–0.73; P =.05; Figure 3 ; Table 3 ).