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Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish.

Redox Biol · 2023 · PMC10031532 · PMID 36934645

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Although Nrf2 dependence was unclear, there was an overall trend indicating that these visual cycle genes were downregulated in keap1a;keap1b- DKO larvae ( Fig. 4 C).

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