a decreasing trendp < .05
3.5 Gene expression The qRT-PCR results showed that memantine ( p < .05) and pre-treatment with Augmentin ( p < .01) significantly increased PSEN2 expression in scopolamine-induced AD rats ( Figure 6A ), while ITPKB expression showed a decreasing trend in the AD rats receiving memantine ( p < .05) and pre-treatment with Augmentin ( p < .0001) (see Figure 6B ).