Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo.

PLoS One · 2023 · PMC10035898 · PMID 36952536

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a slight trendno p-value reported

Only tumors generated from LS174T CRC cells showed a slight trend toward tumor size reduction in the presence of the drug combination compared to single agents.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.