A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study.

Sci Rep · 2023 · PMC10036612 · PMID 36959271

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a decreasing trendno p-value reported

S3 gives the distribution of the FamRS in T2D cases stratified in 10-year age-groups, showing a decreasing trend for increasing age.

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highly significantno p-value reported

The effect of the PGS was quite stable and highly significant across all models, with ORs ranging from 5.95 to 6.21 for prevalent and 1.66 and 1.68 for incident cases (per 1 sd increase).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.