Persistent SARS-CoV-2-specific immune defects in kidney transplant recipients following third mRNA vaccine dose.

Am J Transplant · 2023 · PMC10037915 · PMID 36966905

Europe PMC DOI

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Multivariable modeling of day 30 anti-RBD level in KTRs incorporating TCR measures revealed a positive association of day 30 spike-specific CD4 + T cell breadth (aRatio = 1.05 2.05 4.02 [per 1 log], P = .037) and a highly significant negative association of high-dose MMF (aRatio= 0.02 0.06 0.18 , P < .001) after accounting for transplant vintage.

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