Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia.

Nat Commun · 2023 · PMC10039905 · PMID 36966135

Europe PMC DOI

hedged sentence

0.0529

closest p · 1.1× alpha

0.0529

boldest claim

The sentences

borderline significanceP = 0.0529so close (0.05 < p ≤ 0.1)

Chromosome 8 displayed borderline significance ( P = 0.0529; two-sided exact binomial test) for fewer cases with subclonal UPID/trisomy than expected (Supplementary Table 2 ), possibly indicating that some cases were gaining an extra chromosome from a disomy, in line with positive selection.

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