Improvement of loperamide-hydrochloride-induced intestinal motility disturbance by <i>Platycodon grandiflorum</i> polysaccharides through effects on gut microbes and colonic serotonin.

The results demonstrated an increasing trend in the abundance of Roseburia ( p < 0.05), Butyricimonas ( p < 0.05), and Ruminiclostridium ( p < 0.001), in PGP-H group compare with their abundance in the model group, with no discernible difference between the model and control groups ( Figures 7A–C ).

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