Plasma Glial Fibrillary Acidic Protein Is Associated with 18F-SMBT-1 PET: Two Putative Astrocyte Reactivity Biomarkers for Alzheimer's Disease.

J Alzheimers Dis · 2023 · PMC10041433 · PMID 36776057

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hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

a trend towards significancep = 0.052so close (0.05 < p ≤ 0.1)

However, after adjusting for age, sex, APOE ɛ4 carrier status, and insoluble Aβ, plasma GFAP was significantly associated with 18 F-SMBT-1 PET signal only in the supramarginal gyrus (β= 0.215, p = 0.038), with a trend towards significance observed in the posterior cingulate (β= 0.190, p = 0.052) and lateral temporal (β= 0.174, p = 0.068) regions ( Table 2 ).

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