The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR.

Biology (Basel) · 2023 · PMC10045213 · PMID 36979056

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an increasing trendno p-value reported

In detail, the profile of the R g of the p75NTR/NGFR100W complex is characterized by an increasing trend with consistent variations and a mean value of 26.63 ± 0.22 Å.

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