The Vault Complex Is Significantly Involved in Therapeutic Responsiveness of Endocrine Tumors and Linked to Autophagy under Chemotherapeutic Conditions.

Subsequent experiments revealed that TNFα treatment also resulted in a highly significant accumulation of vault RNA1-1 in the cell culture supernatants of BON cells, while no such effect was detectable for therapeutically unresponsive NCI-H295R cells under these conditions ( Figure 2 L–N). 3.3.

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