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Intranasal Delivery of miR133b in a NEO100-Based Formulation Induces a Healing Response in Spinal Cord-Injured Mice.

Cells · 2023 · PMC10047048 · PMID 36980272

2
hedged sentences
0.2300
closest p · 4.6× alpha
0.2300
boldest claim

The sentences

a decreasing trendp = 0.23not close (p > 0.1)
As shown in Figure 8 A, mice that received miR133b delivered via nasal route showed a decreasing trend, approximately 16%, in Col1a1 expression level when compared to the control treated group ( Figure 8 Ai, t -test, p = 0.23).

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an increasing trendno p-value reported
At 240 min, there was an increasing trend in miR133b level in both miR133b/Ago2 alone and miR133b/Ago2 co-delivered with NEO100 such as: 3.14-fold change vs. 3.07-fold-change, respectively of these groups when compared to the injury only group ( Figure 4 I).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.