Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot Study.

Genes (Basel) · 2023 · PMC10048253 · PMID 36980815

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

borderline significancep = 0.05actually significant

The analysis showed a higher risk of developing OP (OR = 1.81, 95% CI 0.99–3.31) in carriers of the homozygous variant (A/A) or heterozygous (G/A) genotypes of the rs11568820 ( Cdx2 ) polymorphism, although with a borderline significance ( p = 0.05).

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