CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival.

Front Cell Infect Microbiol · 2023 · PMC10050696 · PMID 37009497

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hedged sentence

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closest p · 0.0× alpha

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boldest claim

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highly significantP < 0.0001actually significant

A highly significant knockdown efficiency of murT was found with sgRNA1- murT comparing with WT ATc (53.5-fold; P < 0.0001), PLJR962 ATc (44.6-fold; P < 0.0001) or the respective uninduced mutant (57-fold; P < 0.0001).

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