The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implications for spinocerebellar ataxia type 3 (SCA3) studies using <i>Drosophila melanogaster</i> mutants.

Front Mol Neurosci · 2023 · PMC10050893 · PMID 37008788

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highly significantp < 0.00001actually significant

Nevertheless, a highly significant correlation (Pearson’s correlation coefficient R = 0.968; p < 0.00001) is observed between the frequency of usage of an ataxin-3 amino acid site as a binding site in the two datasets.

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