Elevated Bile Acid Is Associated with Worsened Impaired Glucose Homeostasis in Pancreatic Ductal Adenocarcinoma Patients with Extrahepatic Cholestasis through Increased Hepatic Insulin Clearance.

A decreasing trend was observed when comparing preoperative and postoperative fasting and 2 h postprandial plasma glucose levels, HIC, and 2 h postprandial HIC levels in four of five patients with elevated bile acid levels, but not in preoperative normal bile acid patients ( p < 0.05, Figure 4 A–D).

also in 47,180 other papers