Beneficial Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease (NAFLD) Progression in the Zebrafish Model.

The fact that 1,25(OH) 2 D 3 significantly inhibited lipid accumulation in cells cultured in a steatosis-inducing medium ( Figure 4 ) corroborated the involvement of the genes and metabolic pathways identified in the zebrafish model ( Figure 3 and Supplementary Tables S1 and S3 ) and the idea that these pathways might be significant targets for preventing and treating NAFLD in humans.

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