Intrathecal Pseudodelivery of Drugs in the Therapy of Neurodegenerative Diseases: Rationale, Basis and Potential Applications.

Pharmaceutics · 2023 · PMC10059785 · PMID 36986629

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may be significantno p-value reported

Conversely, if the MW is less than 450 Daltons and the drug forms seven or fewer hydrogen bonds with water, then its transport through the BBB may be significant, provided that it is not a substrate for an active efflux transporter.

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