Determining the mechanism of action of the Qishan formula against lung adenocarcinoma by integration of network pharmacology, molecular docking, and proteomics.

Medicine (Baltimore) · 2023 · PMC10063309 · PMID 37000102

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highly significantno p-value reported

[ 46 ] The pathway-target network we constructed showed that the PI3K/Akt pathway (hsa04151) was highly significant, and previously predicted key targets ( TP53, PIK3R1, MAPK3, MAPK1, HSP90AA1, PIK3CA, HRAS , and AKT1 ) were mainly enriched in the PI3K/Akt pathway.

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