Subanaesthetic single-dose ketamine as an adjunct to opioid analgesics for acute pain management in the emergency department: a systematic review and meta-analysis.

BMJ Open · 2023 · PMC10069507 · PMID 36972961

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an increasing trendno p-value reported

An increasing trend between dose of adjuvant SDK and risk of dysphoria was demonstrated when SDK was administered at 0.15 mg/kg (RR 4.34; 95% CI 0.95 to 19.79) and 0.3 mg/kg (RR 12.01; 95% CI 2.32 to 62.06), compared with opioids alone.

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