Caspase-8 is required for HSV-1-induced apoptosis and promotes effective viral particle release via autophagy inhibition.

Cell Death Differ · 2023 · PMC10070401 · PMID 36418547

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highly significantp = 1.42 × 10 -10actually significant

A quantitative analysis of LC3 and HSV-1-gD co-staining revealed a highly significant ( p = 1.42 × 10 -10 ) 4.5-fold increment of the Mean Colocalization Index (CI) in infected caspase-8−/− as compared to wt MEFs (Fig. 7D ).

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