Therefore, the placental hyperplasia frequently observed in SCNT embryos could be partially improved by farrerol, and this improvement manifested a reduction in weight, a compact structure, and an efficient compression of the spongiotrophoblast (ST) layer, in which the effect by rescued expression of canonical and noncanonical imprints might be significant.
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Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer.
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