highly significantP =0.0245
Of note, 3-year OS and PFS in fit/intermediate versus frail patients showed highly significant differences of 86% (95% CI: 81-90) versus 70% (95% CI: 47-85) and 57% (95% CI: 50-63) versus 21% (95% CI: 6-41), respectively ( P =0.0245/ P <0.0001).