Barely Significant
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Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

Genome Med · 2023 · PMC10074346 · PMID 37020259

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0.0001
closest p · 0.0× alpha
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highly significantP = 1.08 × 10 −4actually significant
0 controls), but the association signal remained highly significant, with a much higher odds ratio (OR = 27.68 [95% CI 1.5–528.7], P = 1.08 × 10 −4 ) (Table 3 ).

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