The effect of TEA on water permeability in cells and tissues that express high levels of AQP1 channels is likely to be significant, given the substantial amount of water that can be moved across AQP1-expressing epithelia (for example, see data on descending thin limbs in Fig. 3 ).
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Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line.
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