When it comes to the other three studied SNPs, associations with harmful alcohol use failed to reach significance.
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Associated and intermediate factors between genetic variants of the dopaminergic D2 receptor gene and harmful alcohol use in young adults.
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The sentences
While the results were highly significant, the proportion of variance in alcohol dependence explained by the PRS‐MDD was small, suggesting that the contribution of shared genetic susceptibility to major depressive disorder and alcohol dependence comorbidity is significant but modest.