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Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial.

BMC Med · 2023 · PMC10079489 · PMID 37024868

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a decreasing trendno p-value reported
In contrast to the NF54 comparator trial, however, where anti-sporozoite titers against NF54, NF135, and NF175 continued to increase following immunizations 2 and 3, in cohort A participants’ sera, we observed a decreasing trend after an initial seroconversion following the first immunization (Fig. 5 ).

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