Infection-related hospitalisation in young adults with systemic lupus erythematosus: data from the National Inpatient Sample.

Lupus Sci Med · 2023 · PMC10083864 · PMID 37019477

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a decreasing trendno p-value reported

A decreasing trend for pneumonia and a significantly increasing trend for sepsis were observed, with sepsis becoming the most common hospitalised infection around 2011.

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an increasing trendno p-value reported

Changes in coding methods for sepsis (with upcoding for sepsis) could also have contributed to an increasing trend over time, and sepsis itself could have been the result of an initial pneumonia or other infections. 24 It is not possible to determine the extent to which this could have happened and the specific causative organisms from the NIS database.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.