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Sericin/Nano-Hydroxyapatite Hydrogels Based on Graphene Oxide for Effective Bone Regeneration via Immunomodulation and Osteoinduction.

Int J Nanomedicine · 2023 · PMC10084881 · PMID 37051313

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extremely significantno p-value reported
More importantly, the combination of nHAP and sericin in the nanocomposite hydrogel further stimulated osteogenesis and bone regrowth, illustrating that the synergistic relationship between the direct osteogenesis activity of nHAP and the immune-induced osteogenesis effect of sericin was extremely significant for bone defect healing.

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