Nose-to-brain delivery of self-assembled curcumin-lactoferrin nanoparticles: Characterization, neuroprotective effect and <i>in vivo</i> pharmacokinetic study.

Front Bioeng Biotechnol · 2023 · PMC10084992 · PMID 37051277

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an increasing trendno p-value reported

Meanwhile, we found that the particle size of CUR-LF NPs did not significantly change within 4 h in each culture system, but the PDI showed an increasing trend. 3.3 In vitro release behaviors Dialysis methods are frequently used for the simulation of the in vitro release kinetics of nanoparticle-based drug delivery systems ( Yu et al., 2019 ).

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