The Effects and Pathogenesis of PM2.5 and Its Components on Chronic Obstructive Pulmonary Disease.

Int J Chron Obstruct Pulmon Dis · 2023 · PMC10086390 · PMID 37056681

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a decreasing trendno p-value reported

114 Besides, in the lungs of COPD rats exposed to PM2.5, there was a decreasing trend in the expression of the Nrf2 protein and its downstream component heme oxygenase-1 (HO-1). 115 The transcription factor Nrf2, which is inversely correlated with the severity of COPD, controls the majority of antioxidants. 116 The primary source of endogenous ROS in mitochondria. 117 Damage to redo

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