highly significantp < 0.0001
Improvements were highly significant compared to baseline for nasolabial folds (mean D0: 2.7 (0.4) vs. mean D540: 1.7 (0.6), p < 0.0001) and marionette lines (mean D0: 2.6 (0.4) vs. mean D540: 1.7 (0.7), p < 0.0001) at 540 days post‐injection and at 450 days post‐injection for lips (mean D0: 1.0 (0.5) vs. mean D450: 1.2 (0.5), p = 0.0326).