Larger effect size in composite kidney outcomes than in major cardiovascular events associated with sodium-glucose cotransporter-2 (SGLT2) inhibitors compared with glucagon-like peptide-1 receptor agonists (GLP-1RAs): A pooled analysis of type 2 diabetes trials.

Diabetes Obes Metab · 2023 · PMC10087851 · PMID 36057779

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a trend towards significanceP = 0.07so close (0.05 < p ≤ 0.1)

In addition, differences seemed greater for trials that included a run‐in period (rHR 0.78, 95% CI 0.68 to 0.90) than those which did not (rHR 0.93, 95% CI 0.82 to 1.05), with a trend towards significance in the interaction test ( P = 0.07).

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