Testosterone treatment combined with exercise to improve muscle strength, physical function and quality of life in men affected by inclusion body myositis: A randomised, double-blind, placebo-controlled, crossover trial.

PLoS One · 2023 · PMC10089314 · PMID 37040372

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significantp = 0.06so close (0.05 < p ≤ 0.1)

A previous study of oxandrolone, a 17α-alkylated androgen, versus placebo in 60 participants with IBM reported a borderline significant effect on whole- and upper body strength (p = 0.06 for whole body maximal voluntary isometric contraction testing (MVICT), p = 0006 for upper extremity MVICT, p < 0.001 for stair climbing) [ 14 ].

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